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Our mission is clear—to protect people from respiratory illness through science-backed, drug-free nasal products.
Meet our Scientists
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Dr. Jeffrey Karp, PhD
Professor at Harvard Medical School
Dr. Karp is a bioengineer who has spent 30+ years creating advanced biomaterials and is recognized as a leader in bioinspired medical innovation.
Technologies developed in the Karp Lab include regenerative therapeutics, tissue adhesives for nerve reconstruction and hernia repair, and auto-stopping needles.
Dr. Karp has published over 125 peer-reviewed papers with >32,000 citations. He has over 100 issued or pending patents. Most recently, Jeff received the highest award from the Society For Biomaterials for innovation – the Clemson Award for Applied Research. Technology Review Magazine (TR35) also recognized Karp as one of the world's top innovators.
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Dr. Nitin Joshi, PhD
Assistant Professor at Harvard Medical School
Dr. Joshi is a bioengineer who has spent 15+ years working at the intersection of chemistry, material science, biology, and medicine.
His lab's highly interdisciplinary and collaborative research focuses on developing translatable drug-delivery technologies, leading to multiple patents, many of which are issued to biotech companies and advancing through clinical trials.
Dr. Joshi’s research has led to 30+ peer-reviewed publications in top-tier journals, including Nature Communications, Science Advances, Nanotoday, Biomaterials, and Journal of Controlled Release. He has received numerous awards, including MIT’s Technology Review Award, Lockheed Martin Innovation Award, Boston Patent Law Association (BPLA) 2020 Invented Here! and Stepping Strong COVID-19 Research Award.
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The making of Profi™
When the pandemic hit, our scientists were part of a working group tasked to come up with a backup plan in case Brigham and Women's Hospital ran out of n95 masks.
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Driven by science
A stream of discoveries taught us that the nose is the primary entry point for germs capable of causing respiratory problems in the sinuses, airways, and lungs. Germs are released into the air when individuals cough, sneeze, talk, or even breathe. These particles can linger for hours and travel through indoor ventilation systems.
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Started with a need
Hand hygiene is important, but based on science, we now know that the air we breathe matters! While masking can be effective, most masks have gaps that allow 40% of the air to be unfiltered. So, we accelerated forward to reimagine a solution that addresses the problem at the gate.
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Profi™ is born
At the time we were already developing a nasal spray platform to help treat Multiple Sclerosis and help maximize the duration of formulation contact with the nasal lining over an 8+ hour period. We began exploring natural and non-drug molecules, iterating across hundreds of ingredients and combinations to identify the right amounts to optimize for sprayability, safety, and effectiveness.
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Real science, ensured quality
Today, Profi™ is manufactured in the USA under cGMP regulations enforced by the FDA. All ingredients are USP-certified to ensure that each Profi™ meets the specifications for potency, quality & safety. Our manufacturing facility, warehouses, and shipping centers are inspected regularly. We are committed to transparency, so you know what you’re getting every time you buy.
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